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BAKER BROS. ADVISORS LP

NEW YORK, NY · CIK 0001263508

Portfolio Value: $11.44B
Positions: 120
Period: 2017-06-30
Filed: 2017-08-14
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021Q2 2021Q1 2021Q4 2020Q3 2020Q2 2020Q1 2020Q4 2019Q3 2019Q2 2019Q1 2019Q4 2018Q3 2018Q2 2018Q1 2018Q4 2017Q3 2017Q2 2017Q1 2017Q4 2016Q3 2016Q2 2016Q1 2016Q4 2015Q3 2015Q2 2015Q1 2015Q4 2014

Portfolio Value

$11.44B

Positions

120

New

5

Increased

24

Decreased

10

Sold Out

97

BAKER BROS. ADVISORS LP Q2 2017 13F Filing Summary

BAKER BROS. ADVISORS LP (NEW YORK, NY) reported a portfolio value of $11.44B across 120 positions in their Q2 2017 SEC 13F filing (period ending 2017-06-30). Top holdings include INCY ($4.30B), SE ($2.37B), Alexion Pharmaceuticals, Inc. ($1.04B). The top 10 positions account for 87.7% of the portfolio. This quarter saw 5 new positions, 24 increases, 10 reductions, 97 complete exits. Notable new buys: Albireo Pharma, Inc. ($4.12M), GNTLF ($3.67M), THCH ($3.67M). Notable exits: BMRN, THCH, Dermira, Inc..

All Holdings

#StockValue↓WeightChange
1
INCYIncyte Corporation
COM
$4.30B
37.57%
+0.1%
2
SESeattle Genetics, Inc.
COM
$2.37B
20.68%
+0.0%
3
Alexion Pharmaceuticals, Inc.
COM
$1.04B
9.10%
+30.7%
4
ACADACADIA Pharmaceuticals Inc.
COM
$720.11M
6.30%
-
5
BMRNBioMarin Pharmaceutical Inc.
COM
$536.35M
4.69%
+22.9%
6
THCHGenomic Health, Inc.
COM
$448.54M
3.92%
+0.1%
7
DBV Technologies S.A.
SPONSORED ADR
$196.75M
1.72%
-
8
ONCBeiGene, Ltd.
SPONSORED ADR
$165.29M
1.45%
-
9
Aquinox Pharmaceuticals, Inc.
COM
$153.84M
1.34%
-
10
Achaogen, Inc.
COM
$104.40M
0.91%
+4.8%
11
AMRNAmarin Corporation plc
SPONSORED ADR NEW
$91.36M
0.80%
+0.1%
12
PPLAdvanced Accelerator Applications S.A.
SPONSORED ADS
$86.73M
0.76%
-
13
PARSpark Therapeutics, Inc.
COM
$78.76M
0.69%
-
14
Invitae Corporation
COM
$69.68M
0.61%
-
15
BCRXBioCryst Pharmaceuticals, Inc.
COM
$65.14M
0.57%
-
16
Bellicum Pharmaceuticals, Inc.
COM
$58.78M
0.51%
-
17
AveXis, Inc.
COM
$51.35M
0.45%
+25.0%
18
EXELExelixis, Inc.
COM
$51.28M
0.45%
-20.0%
19
ASNDAscendis Pharma A/S
SPONSORED ADR
$48.62M
0.43%
+29.6%
20
NVAXNovavax, Inc.
NOTE 3.75% 2/1/2023
$46.43M
0.41%
-
21
HRTXHeron Therapeutics, Inc.
COM
$38.55M
0.34%
-
22
SGMOSangamo Therapeutics, Inc.
COM
$36.20M
0.32%
-9.2%
23
BLUEbluebird bio, Inc.
COM
$31.67M
0.28%
-14.2%
24
THCHAcorda Therapeutics, Inc.
NOTE 1.75% 6/15/2021
$29.98M
0.26%
-
25
Versartis, Inc.
COM
$28.98M
0.25%
-
26
NBIXNeurocrine Biosciences, Inc.
COM
$28.37M
0.25%
-31.1%
27
CERSCerus Corporation
COM
$25.71M
0.22%
-21.5%
28
ImmunoGen, Inc.
COM
$21.44M
0.19%
-
29
PRGProgenics Pharmaceuticals, Inc.
COM
$21.39M
0.19%
-
30
HALOHalozyme Therapeutics, Inc.
COM
$20.27M
0.18%
+13.6%
31
GLPGGalapagos NV
SPONSORED ADR
$19.89M
0.17%
-
32
XNCRXencor, Inc.
COM
$18.41M
0.16%
-
33
MRUSMerus N.V.
COM
$18.39M
0.16%
-
34
Idera Pharmaceuticals, Inc.
COM NEW
$17.71M
0.15%
+0.1%
35
NeuroDerm Ltd.
ORD SHS
$17.09M
0.15%
-
36
NTLAIntellia Therapeutics, Inc.
COM
$16.99M
0.15%
-
37
SAGESage Therapeutics, Inc.
COM
$16.59M
0.15%
-
38
AERIEURAerie Pharmaceuticals, Inc.
COM
$15.73M
0.14%
-
39
La Jolla Pharmaceutical Company
COM PAR $.0001 2
$15.03M
0.13%
+33.1%
40
CPRXCatalyst Pharmaceuticals, Inc.
COM
$14.08M
0.12%
-
41
THCHAimmune Therapeutics, Inc.
COM
$13.86M
0.12%
-
42
BMRNBioMarin Pharmaceutical Inc.
NOTE 0.75% 10/15/2018
$13.55M
0.12%
-
43
ARRYArray BioPharma Inc.
COM
$13.27M
0.12%
-
44
Aegerion Pharmaceuticals, Inc.
NOTE 2.0% 8/15/2019
$11.55M
0.10%
-12.1%
45
Foamix Pharmaceuticals Ltd.
SHS
$11.45M
0.10%
-
46
OLOLoxo Oncology, Inc.
COM
$11.09M
0.10%
+0.4%
47
ABEOAbeona Therapeutics Inc.
COM
$10.78M
0.09%
-
48
Ignyta, Inc.
COM
$9.27M
0.08%
+56.9%
49
SYRSSyros Pharmaceuticals, Inc.
COM
$9.25M
0.08%
+181.1%
50
LGNDLigand Pharmaceuticals Incorporated
COM NEW
$8.91M
0.08%
-
Showing 1-50 of 120

Position Changes

StockValueShares
Albireo Pharma, Inc.
$4.12M200,000
GNTLFNewLink Genetics Corporation
$3.67M500,000
THCHNabriva Therapeutics plc
$3.67M350,000
OVIDOvid Therapeutics Inc.
$3.50M333,333
ARGXargenx SE
$2.12M100,000